It happened years ago when sound cards moved from ISA slots to PCI as the cards and what they did became more complex. Could a similar shift be about to happen? Creative Technology, maker of the defacto-standard in PC audio cards, the Sound Blaster line, were showing off their first audio card for the PCI Express bus at CES 2007.
Pretty soon there won't be any devices left that use the old PCI bus. PCIe could become the universal bus for expansion cards in PCs in the next few years, with graphics card makers already migrating to it, away from the aging AGP standard.